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Photo-induced synthesis, structure and in vitro bioactivity of a natural cyclic peptide Yunnanin A analog

A cyclic analog of natural peptide Yunnanin A was synthesized via photoinduced single electron transfer reaction (SET) in the paper. The resulting compound exhibited potent bioactivity (with IC(50) values 29.25 μg mL(−1) against HepG-2 cell lines and 65.01 μg mL(−1) against HeLa cell lines), but alm...

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Detalles Bibliográficos
Autores principales: Jiang, Shitian, Zhao, Lishuang, Wu, Jingwan, Bao, Yujun, Wang, Zhiqiang, Jin, Yingxue
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2019
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047273/
https://www.ncbi.nlm.nih.gov/pubmed/35492554
http://dx.doi.org/10.1039/c9ra09163g