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Systematic evaluation of colorectal cancer organoid system by single-cell RNA-Seq analysis

BACKGROUND: Patient-derived organoid culture is a powerful system for studying the molecular mechanisms of cancers, especially colorectal cancer (CRC), one of the most prevalent cancers worldwide. There are two main types of 3D culture methods for colonic cells, but the similarities and differences...

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Detalles Bibliográficos
Autores principales:	Wang, Rui, Mao, Yunuo, Wang, Wendong, Zhou, Xin, Wang, Wei, Gao, Shuai, Li, Jingyun, Wen, Lu, Fu, Wei, Tang, Fuchou
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047329/ https://www.ncbi.nlm.nih.gov/pubmed/35484598 http://dx.doi.org/10.1186/s13059-022-02673-3

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