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Technical considerations in PCR-based assay design for diagnostic DNA methylation cancer biomarkers

BACKGROUND: DNA methylation biomarkers for early detection, risk stratification and treatment response in cancer have been of great interest over the past decades. Nevertheless, clinical implementation of these biomarkers is limited, as only < 1% of the identified biomarkers is translated into a...

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Detalles Bibliográficos
Autores principales:	Massen, Maartje, Lommen, Kim, Wouters, Kim A. D., Vandersmissen, Johan, van Criekinge, Wim, Herman, James G., Melotte, Veerle, Schouten, Leo J., van Engeland, Manon, Smits, Kim M.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2022
Materias:	Methodology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047347/ https://www.ncbi.nlm.nih.gov/pubmed/35477541 http://dx.doi.org/10.1186/s13148-022-01273-z

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