Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides

A new heterogeneous catalytic system (Ti-superoxide/saccharin/TBHP) has been developed that efficiently catalyzes oxidative amidation of aldehydes to produce various primary amides. The protocol employs saccharin as amine source and was found to tolerate a wide range of substrates with different fun...

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Autores principales: Kamble, Rohit B., Mane, Kishor D., Rupanawar, Bapurao D., Korekar, Pranjal, Sudalai, A., Suryavanshi, Gurunath
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047451/
https://www.ncbi.nlm.nih.gov/pubmed/35494431
http://dx.doi.org/10.1039/c9ra10413e
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author Kamble, Rohit B.
Mane, Kishor D.
Rupanawar, Bapurao D.
Korekar, Pranjal
Sudalai, A.
Suryavanshi, Gurunath
author_facet Kamble, Rohit B.
Mane, Kishor D.
Rupanawar, Bapurao D.
Korekar, Pranjal
Sudalai, A.
Suryavanshi, Gurunath
author_sort Kamble, Rohit B.
collection PubMed
description A new heterogeneous catalytic system (Ti-superoxide/saccharin/TBHP) has been developed that efficiently catalyzes oxidative amidation of aldehydes to produce various primary amides. The protocol employs saccharin as amine source and was found to tolerate a wide range of substrates with different functional groups. Moderate to excellent yields, catalyst reusability and operational simplicity are the main highlights. A possible mechanism and the role of the catalyst in oxidative amidation have also been discussed.
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spelling pubmed-90474512022-04-28 Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides Kamble, Rohit B. Mane, Kishor D. Rupanawar, Bapurao D. Korekar, Pranjal Sudalai, A. Suryavanshi, Gurunath RSC Adv Chemistry A new heterogeneous catalytic system (Ti-superoxide/saccharin/TBHP) has been developed that efficiently catalyzes oxidative amidation of aldehydes to produce various primary amides. The protocol employs saccharin as amine source and was found to tolerate a wide range of substrates with different functional groups. Moderate to excellent yields, catalyst reusability and operational simplicity are the main highlights. A possible mechanism and the role of the catalyst in oxidative amidation have also been discussed. The Royal Society of Chemistry 2020-01-02 /pmc/articles/PMC9047451/ /pubmed/35494431 http://dx.doi.org/10.1039/c9ra10413e Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Kamble, Rohit B.
Mane, Kishor D.
Rupanawar, Bapurao D.
Korekar, Pranjal
Sudalai, A.
Suryavanshi, Gurunath
Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides
title Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides
title_full Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides
title_fullStr Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides
title_full_unstemmed Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides
title_short Ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides
title_sort ti-superoxide catalyzed oxidative amidation of aldehydes with saccharin as nitrogen source: synthesis of primary amides
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047451/
https://www.ncbi.nlm.nih.gov/pubmed/35494431
http://dx.doi.org/10.1039/c9ra10413e
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