S-Ketamine Pretreatment Alleviates Anxiety-Like Behaviors and Mechanical Allodynia and Blocks the Pro-inflammatory Response in Striatum and Periaqueductal Gray From a Post-traumatic Stress Disorder Model

This study aims to explore the regulatory effect of S-ketamine on the mechanical allodynia, anxiety-like behaviors and microglia activation in adult male rats exposed to an animal model of post-traumatic stress disorder (PTSD). The rat PTSD model was established by the exposure to single-prolonged s...

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Detalles Bibliográficos
Autores principales: Yang, Shuai, Xu, Ke, Xu, Xuan, Zhu, Jixiang, Jin, Yinan, Liu, Qi, Xu, Rui, Gu, Xiaoping, Liu, Yue, Huang, Yulin, Ma, Zhengliang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047507/
https://www.ncbi.nlm.nih.gov/pubmed/35493953
http://dx.doi.org/10.3389/fnbeh.2022.848232

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