Novel isatin–indole derivatives as potential inhibitors of chorismate mutase (CM): their synthesis along with unexpected formation of 2-indolylmethylamino benzoate ester under Pd–Cu catalysis

A series of novel isatin–indole derivatives has been designed as potential inhibitors of chorismate mutase (CM) that is known to be present in bacteria, fungi and higher plants but not in human. The design was supported by in silico docking studies that predicted strong interactions of these molecul...

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Detalles Bibliográficos
Autores principales: Reddy, Gangireddy Sujeevan, Hossain, Kazi Amirul, Kumar, Jetta Sandeep, Thirupataiah, B., Edwin, Rebecca Kristina, Giliyaru, Varadaraj Bhat, Chandrashekhar Hariharapura, Raghu, Shenoy, G. Gautham, Misra, Parimal, Pal, Manojit
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047634/
https://www.ncbi.nlm.nih.gov/pubmed/35492515
http://dx.doi.org/10.1039/c9ra09236f

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