Omadacycline pharmacokinetics and soft-tissue penetration in diabetic patients with wound infections and healthy volunteers using in vivo microdialysis

OBJECTIVES: We assessed the plasma and soft-tissue pharmacokinetic exposure of omadacycline in infected patients with diabetic foot infection (DFI) and healthy volunteers using in vivo microdialysis. METHODS: Eight patients and six healthy volunteers were enrolled and received an omadacycline IV loa...

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Detalles Bibliográficos
Autores principales: Gill, Christian M, Fratoni, Andrew J, Shepard, Ashley K, Kuti, Joseph L, Nicolau, David P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047675/
https://www.ncbi.nlm.nih.gov/pubmed/35194643
http://dx.doi.org/10.1093/jac/dkac055

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