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NUDT15 Genetic Variants in Chinese Han, Uighur, Kirghiz, and Dai Nationalities

BACKGROUND: Thiopurines are widely used as anti-cancer and immunosuppressant agents, but have a narrow therapeutic index owing to frequent toxicity and life-threatening bone marrow suppression. The nudix hydrolase 15 (NUDT15) genetic polymorphism is strongly associated with the tolerance and myelosu...

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Detalles Bibliográficos
Autores principales:	Zhang, Fang, Amat, Gulbanur, Tang, Yanjing, Chen, Ru, Tian, Xin, Hu, Wenting, Chen, Changcheng, Shen, Shuhong, Xie, Yangyang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pediatrics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047856/ https://www.ncbi.nlm.nih.gov/pubmed/35498806 http://dx.doi.org/10.3389/fped.2022.832363

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