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Amyloid-β Induces Cdh1-Mediated Rock2 Stabilization Causing Neurodegeneration

Alzheimer’s disease (AD) is a neurodegenerative disorder characterized by progressive cognitive decline, which is causally related to the accumulation of abnormally folded amyloid-β (Aβ) peptide and hyperphosphorylated tau protein aggregates. The dendritic spine regulator Rho protein kinase 2 (Rock2...

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Detalles Bibliográficos
Autores principales:	Lapresa, Rebeca, Agulla, Jesus, Gonzalez-Guerrero, Sonia, Bolaños, Juan P., Almeida, Angeles
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2022
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047900/ https://www.ncbi.nlm.nih.gov/pubmed/35496276 http://dx.doi.org/10.3389/fphar.2022.884470

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