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Association between plasma somatic copy number variations and response to immunotherapy in patients with programmed death-ligand 1-negative non-small cell lung cancer

OBJECTIVE: To determine how patients with non-small cell lung cancer (NSCLC) with programmed death-ligand 1 (PD-L1)-negative and/or a low tumor mutation burden status benefit from immune checkpoint inhibitors (ICI). METHODS: We determined the plasma cell-free DNA profiles of 25 patients with PD-L1-n...

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Detalles Bibliográficos
Autores principales:	Zhang, Xiaochen, Wang, Yina, Xiang, Jingjing, Zhao, Pan, Xun, Yanping, Zhang, Shirong, Xu, Nong
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	SAGE Publications 2022
Materias:	Pre-Clinical Research Report
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9047987/ https://www.ncbi.nlm.nih.gov/pubmed/35466753 http://dx.doi.org/10.1177/03000605221093222

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