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Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection

BACKGROUND: Acute type A aortic dissection (ATAAD) is a life-threatening disease associated with high morbidity and mortality. AIM: To evaluate the diameter of dissected ascending aorta in patients diagnosed with ATAAD and whether the aortic diameter is associated with preoperative adverse events. M...

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Autores principales: Samanidis, George, Kanakis, Meletios, Georgiou, Charalampos, Perreas, Konstantinos
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Baishideng Publishing Group Inc 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048272/
https://www.ncbi.nlm.nih.gov/pubmed/35582464
http://dx.doi.org/10.4330/wjc.v14.i4.231
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author Samanidis, George
Kanakis, Meletios
Georgiou, Charalampos
Perreas, Konstantinos
author_facet Samanidis, George
Kanakis, Meletios
Georgiou, Charalampos
Perreas, Konstantinos
author_sort Samanidis, George
collection PubMed
description BACKGROUND: Acute type A aortic dissection (ATAAD) is a life-threatening disease associated with high morbidity and mortality. AIM: To evaluate the diameter of dissected ascending aorta in patients diagnosed with ATAAD and whether the aortic diameter is associated with preoperative adverse events. METHODS: A total of 108 patients diagnosed with ATAAD who underwent emergency operation under hypothermic circulatory arrest were enrolled in this study. Demographic characteristics and perioperative data were recorded. In all patients, preoperative chest and abdomen computed tomography (CT) scans were performed. RESULTS: Median age of the patients was 61.5 (52.5-70.5) years and median body mass index (BMI) was 28.2 (25.1-32.6) cm(2). The number of female patients was 37 (25%). Median diameter of the ascending aorta was 5.0 (4.5-6) cm and 53.8% of the patients had an aortic diameter < 5.0 cm, while 32.3% of the patients had an aortic diameter of 4.5cm and 72.0% had an ascending aorta diameter < 5.5 cm. The diameter of the ascending aorta did not differ in patients with vs without preoperative adverse events: Preoperative neurological dysfunction (P = 0.53) and hemodynamic instability (P = 0.43). Median age of patients with preoperative hemodynamic instability was 65 (57.5-74) years, while it was 60 (51-68) years in patients without (P = 0.04) CONCLUSION: Although current guidelines suggest replacing the ascending aorta with a diameter > 5.5 cm, most of the patients with ATAAD had an aortic diameter of less than 5.5 cm. The diameter of the ascending aorta in patients diagnose with ATAAD is not associated with preoperative adverse events.
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spelling pubmed-90482722022-05-16 Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection Samanidis, George Kanakis, Meletios Georgiou, Charalampos Perreas, Konstantinos World J Cardiol Observational Study BACKGROUND: Acute type A aortic dissection (ATAAD) is a life-threatening disease associated with high morbidity and mortality. AIM: To evaluate the diameter of dissected ascending aorta in patients diagnosed with ATAAD and whether the aortic diameter is associated with preoperative adverse events. METHODS: A total of 108 patients diagnosed with ATAAD who underwent emergency operation under hypothermic circulatory arrest were enrolled in this study. Demographic characteristics and perioperative data were recorded. In all patients, preoperative chest and abdomen computed tomography (CT) scans were performed. RESULTS: Median age of the patients was 61.5 (52.5-70.5) years and median body mass index (BMI) was 28.2 (25.1-32.6) cm(2). The number of female patients was 37 (25%). Median diameter of the ascending aorta was 5.0 (4.5-6) cm and 53.8% of the patients had an aortic diameter < 5.0 cm, while 32.3% of the patients had an aortic diameter of 4.5cm and 72.0% had an ascending aorta diameter < 5.5 cm. The diameter of the ascending aorta did not differ in patients with vs without preoperative adverse events: Preoperative neurological dysfunction (P = 0.53) and hemodynamic instability (P = 0.43). Median age of patients with preoperative hemodynamic instability was 65 (57.5-74) years, while it was 60 (51-68) years in patients without (P = 0.04) CONCLUSION: Although current guidelines suggest replacing the ascending aorta with a diameter > 5.5 cm, most of the patients with ATAAD had an aortic diameter of less than 5.5 cm. The diameter of the ascending aorta in patients diagnose with ATAAD is not associated with preoperative adverse events. Baishideng Publishing Group Inc 2022-04-26 2022-04-26 /pmc/articles/PMC9048272/ /pubmed/35582464 http://dx.doi.org/10.4330/wjc.v14.i4.231 Text en ©The Author(s) 2022. Published by Baishideng Publishing Group Inc. All rights reserved. https://creativecommons.org/licenses/by-nc/4.0/This article is an open-access article that was selected by an in-house editor and fully peer-reviewed by external reviewers. It is distributed in accordance with the Creative Commons Attribution NonCommercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited and the use is non-commercial. See: https://creativecommons.org/Licenses/by-nc/4.0/
spellingShingle Observational Study
Samanidis, George
Kanakis, Meletios
Georgiou, Charalampos
Perreas, Konstantinos
Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection
title Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection
title_full Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection
title_fullStr Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection
title_full_unstemmed Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection
title_short Association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type A aortic dissection
title_sort association of dissected ascending aorta diameter with preoperative adverse events in patients with acute type a aortic dissection
topic Observational Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048272/
https://www.ncbi.nlm.nih.gov/pubmed/35582464
http://dx.doi.org/10.4330/wjc.v14.i4.231
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AT georgioucharalampos associationofdissectedascendingaortadiameterwithpreoperativeadverseeventsinpatientswithacutetypeaaorticdissection
AT perreaskonstantinos associationofdissectedascendingaortadiameterwithpreoperativeadverseeventsinpatientswithacutetypeaaorticdissection