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SGLT inhibitors as antidiabetic agents: a comprehensive review

Diabetes is one of the most common disorders that substantially contributes to an increase in global health burden. As a metabolic disorder, diabetes is associated with various medical conditions and diseases such as obesity, hypertension, cardiovascular diseases, and atherosclerosis. In this review...

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Detalles Bibliográficos
Autores principales: Kshirsagar, Rahul P., Kulkarni, Abhishek A., Chouthe, Rashmi S., Pathan, Shahebaaz K., Une, Hemant D., Reddy, G. Bhanuprakash, Diwan, Prakash V., Ansari, Siddique Akber, Sangshetti, Jaiprakash N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048284/
https://www.ncbi.nlm.nih.gov/pubmed/35494673
http://dx.doi.org/10.1039/c9ra08706k
Descripción
Sumario:Diabetes is one of the most common disorders that substantially contributes to an increase in global health burden. As a metabolic disorder, diabetes is associated with various medical conditions and diseases such as obesity, hypertension, cardiovascular diseases, and atherosclerosis. In this review, we cover the scientific studies on sodium/glucose cotransporter (SGLT) inhibitors published during the last decade. Our focus on providing an exhaustive overview of SGLT inhibitors enabled us to present their chemical classification for the first time.