Synthesis of new piperazinyl-pyrrolo[1,2-a]quinoxaline derivatives as inhibitors of Candida albicans multidrug transporters by a Buchwald–Hartwig cross-coupling reaction

Two series of piperazinyl-pyrrolo[1,2-a]quinoxaline derivatives were prepared via a Buchwald–Hartwig cross-coupling reaction and then evaluated for their ability to inhibit the drug efflux activity of CaCdr1p and CaMdr1p transporters of Candida albicans overexpressed in a Saccharomyces cerevisiae st...

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Detalles Bibliográficos
Autores principales: Guillon, Jean, Nim, Shweta, Moreau, Stéphane, Ronga, Luisa, Savrimoutou, Solène, Thivet, Elisabeth, Marchivie, Mathieu, Di Pietro, Attilio, Prasad, Rajendra, Le Borgne, Marc
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048445/
https://www.ncbi.nlm.nih.gov/pubmed/35496110
http://dx.doi.org/10.1039/c9ra09348f

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048445/
https://www.ncbi.nlm.nih.gov/pubmed/35496110
http://dx.doi.org/10.1039/c9ra09348f

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