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Circulating tumor DNA genomic profiling reveals the complicated olaparib-resistance mechanism in prostate cancer salvage therapy: A case report
BACKGROUND: The poly (ADP-ribose) polymerase (PARP) inhibitor olaparib has displayed superior clinical effect in metastatic castration-resistant prostate cancer (mCRPC) patients with the homologous recombination repair (HRR) genes mutations. However, when a patient’s tumor tissue volume is insuffici...
Autores principales: | Yuan, Fang, Liu, Nan, Yang, Ming-Zhen, Zhang, Xiao-Tian, Luo, Hong, Zhou, Hong |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Baishideng Publishing Group Inc
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048572/ https://www.ncbi.nlm.nih.gov/pubmed/35611209 http://dx.doi.org/10.12998/wjcc.v10.i11.3461 |
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