Airway epithelial interferon response to SARS-CoV-2 is inferior to rhinovirus and heterologous rhinovirus infection suppresses SARS-CoV-2 replication

Common alphacoronaviruses and human rhinoviruses (HRV) induce type I and III interferon (IFN) responses important to limiting viral replication in the airway epithelium. In contrast, highly pathogenic betacoronaviruses including SARS-CoV-2 may evade or antagonize RNA-induced IFN I/III responses. In...

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Detalles Bibliográficos
Autores principales: Vanderwall, Elizabeth R., Barrow, Kaitlyn A., Rich, Lucille M., Read, David F., Trapnell, Cole, Okoloko, Oghenemega, Ziegler, Steven F., Hallstrand, Teal S., White, Maria P., Debley, Jason S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048621/
https://www.ncbi.nlm.nih.gov/pubmed/35484173
http://dx.doi.org/10.1038/s41598-022-10763-2

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