Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions

An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A marked difference was observed in the fragmentation efficiency by using conventional Cs-137 vs. pulsed sources.

Detalles Bibliográficos
Autores principales: Barosi, Anna, Dunkel, Petra, Guénin, Erwann, Lalatonne, Yoann, Zeitoun, Philippe, Fitton, Isabelle, Journé, Clément, Bravin, Alberto, Maruani, Antoine, Dhimane, Hamid, Motte, Laurence, Dalko, Peter I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048766/
https://www.ncbi.nlm.nih.gov/pubmed/35497736
http://dx.doi.org/10.1039/c9ra09828c
Descripción
Sumario:An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A marked difference was observed in the fragmentation efficiency by using conventional Cs-137 vs. pulsed sources.

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