Cargando…

Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions

An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A marked difference was observed in the fragmentation efficiency by using conventional Cs-137 vs. pulsed sources.

Detalles Bibliográficos
Autores principales: Barosi, Anna, Dunkel, Petra, Guénin, Erwann, Lalatonne, Yoann, Zeitoun, Philippe, Fitton, Isabelle, Journé, Clément, Bravin, Alberto, Maruani, Antoine, Dhimane, Hamid, Motte, Laurence, Dalko, Peter I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048766/
https://www.ncbi.nlm.nih.gov/pubmed/35497736
http://dx.doi.org/10.1039/c9ra09828c
_version_ 1784696002939191296
author Barosi, Anna
Dunkel, Petra
Guénin, Erwann
Lalatonne, Yoann
Zeitoun, Philippe
Fitton, Isabelle
Journé, Clément
Bravin, Alberto
Maruani, Antoine
Dhimane, Hamid
Motte, Laurence
Dalko, Peter I.
author_facet Barosi, Anna
Dunkel, Petra
Guénin, Erwann
Lalatonne, Yoann
Zeitoun, Philippe
Fitton, Isabelle
Journé, Clément
Bravin, Alberto
Maruani, Antoine
Dhimane, Hamid
Motte, Laurence
Dalko, Peter I.
author_sort Barosi, Anna
collection PubMed
description An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A marked difference was observed in the fragmentation efficiency by using conventional Cs-137 vs. pulsed sources.
format Online
Article
Text
id pubmed-9048766
institution National Center for Biotechnology Information
language English
publishDate 2020
publisher The Royal Society of Chemistry
record_format MEDLINE/PubMed
spelling pubmed-90487662022-04-28 Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions Barosi, Anna Dunkel, Petra Guénin, Erwann Lalatonne, Yoann Zeitoun, Philippe Fitton, Isabelle Journé, Clément Bravin, Alberto Maruani, Antoine Dhimane, Hamid Motte, Laurence Dalko, Peter I. RSC Adv Chemistry An efficient nano-sized delivery system is presented here allowing the immobilized, picolinium-tethered organic ligand to be released by X-ray irradiation. A marked difference was observed in the fragmentation efficiency by using conventional Cs-137 vs. pulsed sources. The Royal Society of Chemistry 2020-01-21 /pmc/articles/PMC9048766/ /pubmed/35497736 http://dx.doi.org/10.1039/c9ra09828c Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Barosi, Anna
Dunkel, Petra
Guénin, Erwann
Lalatonne, Yoann
Zeitoun, Philippe
Fitton, Isabelle
Journé, Clément
Bravin, Alberto
Maruani, Antoine
Dhimane, Hamid
Motte, Laurence
Dalko, Peter I.
Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions
title Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions
title_full Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions
title_fullStr Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions
title_full_unstemmed Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions
title_short Synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed X-ray irradiation conditions
title_sort synthesis and activation of an iron oxide immobilized drug-mimicking reporter under conventional and pulsed x-ray irradiation conditions
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048766/
https://www.ncbi.nlm.nih.gov/pubmed/35497736
http://dx.doi.org/10.1039/c9ra09828c
work_keys_str_mv AT barosianna synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT dunkelpetra synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT gueninerwann synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT lalatonneyoann synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT zeitounphilippe synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT fittonisabelle synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT journeclement synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT bravinalberto synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT maruaniantoine synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT dhimanehamid synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT mottelaurence synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions
AT dalkopeteri synthesisandactivationofanironoxideimmobilizeddrugmimickingreporterunderconventionalandpulsedxrayirradiationconditions