Inhibition of human thrombin by the constituents of licorice: inhibition kinetics and mechanistic insights through in vitro and in silico studies

Thrombin inhibition therapy is a practical strategy to reduce thrombotic and cardiovascular risks via blocking the formation of blood clots. This study aimed to identify naturally occurring thrombin inhibitors from licorice (one of the most popular edible herbs), as well as to investigate their inhi...

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Detalles Bibliográficos
Autores principales: Shi, Cheng-Cheng, Chen, Tian-Ran, Zhang, Qi-Hua, Wei, Ling-Hua, Huang, Chao, Zhu, Ya-Di, Liu, Hai-Bin, Bai, Ya-Kun, Wang, Fang-Jun, Guo, Wen-Zhi, Zhang, Li-Rong, Ge, Guang-Bo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9048847/
https://www.ncbi.nlm.nih.gov/pubmed/35492646
http://dx.doi.org/10.1039/c9ra09203j

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