Cordyceps sinensis-mediated biotransformation of notoginsenoside R1 into 25-OH-20(S/R)-R2 with elevated cardioprotective effect against DOX-induced cell injury

Notoginsenoside R1 is a dammarane saponin in Panax notoginseng with promising cardioprotective effects. The bioactivity–structure relationship of such saponins suggested that the presence of a hydroxyl group at C25 could elevate its performance. To fulfill that goal, bioconversion of notoginsenoside...

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Detalles Bibliográficos
Autores principales: Liu, Jishuang, Xin, Yu, Qiu, Zhidong, Zhang, Qi, He, Tianzhu, Qiu, Ye, Wang, Weinan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049007/
https://www.ncbi.nlm.nih.gov/pubmed/35497008
http://dx.doi.org/10.1039/d2ra01470j

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049007/
https://www.ncbi.nlm.nih.gov/pubmed/35497008
http://dx.doi.org/10.1039/d2ra01470j

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