Rose bengal as photocatalyst: visible light-mediated Friedel–Crafts alkylation of indoles with nitroalkenes in water

A novel and facile visible-light-mediated alkylation of indoles and nitroalkenes has been developed. In this protocol, rose bengal acts as a photosensitizer, and environmentally benign water was used as the green and efficient reaction medium. Indoles reacted smoothly with nitroalkenes under the irr...

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Detalles Bibliográficos
Autores principales: Yu, Zong-Yi, Zhao, Jing-Nan, Yang, Fan, Tang, Xiao-Fei, Wu, Yu-Feng, Ma, Cun-Fei, Song, Bo, Yun, Lei, Meng, Qing-Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049176/
https://www.ncbi.nlm.nih.gov/pubmed/35495280
http://dx.doi.org/10.1039/c9ra09227g
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author Yu, Zong-Yi
Zhao, Jing-Nan
Yang, Fan
Tang, Xiao-Fei
Wu, Yu-Feng
Ma, Cun-Fei
Song, Bo
Yun, Lei
Meng, Qing-Wei
author_facet Yu, Zong-Yi
Zhao, Jing-Nan
Yang, Fan
Tang, Xiao-Fei
Wu, Yu-Feng
Ma, Cun-Fei
Song, Bo
Yun, Lei
Meng, Qing-Wei
author_sort Yu, Zong-Yi
collection PubMed
description A novel and facile visible-light-mediated alkylation of indoles and nitroalkenes has been developed. In this protocol, rose bengal acts as a photosensitizer, and environmentally benign water was used as the green and efficient reaction medium. Indoles reacted smoothly with nitroalkenes under the irradiation of visible-light and generated corresponding 3-(2-nitroalkyl)indoles in moderate to good yields (up to 87%).
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spelling pubmed-90491762022-04-29 Rose bengal as photocatalyst: visible light-mediated Friedel–Crafts alkylation of indoles with nitroalkenes in water Yu, Zong-Yi Zhao, Jing-Nan Yang, Fan Tang, Xiao-Fei Wu, Yu-Feng Ma, Cun-Fei Song, Bo Yun, Lei Meng, Qing-Wei RSC Adv Chemistry A novel and facile visible-light-mediated alkylation of indoles and nitroalkenes has been developed. In this protocol, rose bengal acts as a photosensitizer, and environmentally benign water was used as the green and efficient reaction medium. Indoles reacted smoothly with nitroalkenes under the irradiation of visible-light and generated corresponding 3-(2-nitroalkyl)indoles in moderate to good yields (up to 87%). The Royal Society of Chemistry 2020-01-29 /pmc/articles/PMC9049176/ /pubmed/35495280 http://dx.doi.org/10.1039/c9ra09227g Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Yu, Zong-Yi
Zhao, Jing-Nan
Yang, Fan
Tang, Xiao-Fei
Wu, Yu-Feng
Ma, Cun-Fei
Song, Bo
Yun, Lei
Meng, Qing-Wei
Rose bengal as photocatalyst: visible light-mediated Friedel–Crafts alkylation of indoles with nitroalkenes in water
title Rose bengal as photocatalyst: visible light-mediated Friedel–Crafts alkylation of indoles with nitroalkenes in water
title_full Rose bengal as photocatalyst: visible light-mediated Friedel–Crafts alkylation of indoles with nitroalkenes in water
title_fullStr Rose bengal as photocatalyst: visible light-mediated Friedel–Crafts alkylation of indoles with nitroalkenes in water
title_full_unstemmed Rose bengal as photocatalyst: visible light-mediated Friedel–Crafts alkylation of indoles with nitroalkenes in water
title_short Rose bengal as photocatalyst: visible light-mediated Friedel–Crafts alkylation of indoles with nitroalkenes in water
title_sort rose bengal as photocatalyst: visible light-mediated friedel–crafts alkylation of indoles with nitroalkenes in water
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049176/
https://www.ncbi.nlm.nih.gov/pubmed/35495280
http://dx.doi.org/10.1039/c9ra09227g
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