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A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program
The study aims to determine the shared genetic architecture between COVID-19 severity with existing medical conditions using electronic health record (EHR) data. We conducted a Phenome-Wide Association Study (PheWAS) of genetic variants associated with critical illness (n = 35) or hospitalization (n...
Autores principales: | Verma, Anurag, Tsao, Noah L., Thomann, Lauren O., Ho, Yuk-Lam, Iyengar, Sudha K., Luoh, Shiuh-Wen, Carr, Rotonya, Crawford, Dana C., Efird, Jimmy T., Huffman, Jennifer E., Hung, Adriana, Ivey, Kerry L., Levin, Michael G., Lynch, Julie, Natarajan, Pradeep, Pyarajan, Saiju, Bick, Alexander G., Costa, Lauren, Genovese, Giulio, Hauger, Richard, Madduri, Ravi, Pathak, Gita A., Polimanti, Renato, Voight, Benjamin, Vujkovic, Marijana, Zekavat, Seyedeh Maryam, Zhao, Hongyu, Ritchie, Marylyn D., Chang, Kyong-Mi, Cho, Kelly, Casas, Juan P., Tsao, Philip S., Gaziano, J. Michael, O’Donnell, Christopher, Damrauer, Scott M., Liao, Katherine P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049369/ https://www.ncbi.nlm.nih.gov/pubmed/35482673 http://dx.doi.org/10.1371/journal.pgen.1010113 |
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