A Phenome-Wide Association Study of genes associated with COVID-19 severity reveals shared genetics with complex diseases in the Million Veteran Program

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The study aims to determine the shared genetic architecture between COVID-19 severity with existing medical conditions using electronic health record (EHR) data. We conducted a Phenome-Wide Association Study (PheWAS) of genetic variants associated with critical illness (n = 35) or hospitalization (n...

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Detalles Bibliográficos
Autores principales: Verma, Anurag, Tsao, Noah L., Thomann, Lauren O., Ho, Yuk-Lam, Iyengar, Sudha K., Luoh, Shiuh-Wen, Carr, Rotonya, Crawford, Dana C., Efird, Jimmy T., Huffman, Jennifer E., Hung, Adriana, Ivey, Kerry L., Levin, Michael G., Lynch, Julie, Natarajan, Pradeep, Pyarajan, Saiju, Bick, Alexander G., Costa, Lauren, Genovese, Giulio, Hauger, Richard, Madduri, Ravi, Pathak, Gita A., Polimanti, Renato, Voight, Benjamin, Vujkovic, Marijana, Zekavat, Seyedeh Maryam, Zhao, Hongyu, Ritchie, Marylyn D., Chang, Kyong-Mi, Cho, Kelly, Casas, Juan P., Tsao, Philip S., Gaziano, J. Michael, O’Donnell, Christopher, Damrauer, Scott M., Liao, Katherine P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049369/
https://www.ncbi.nlm.nih.gov/pubmed/35482673
http://dx.doi.org/10.1371/journal.pgen.1010113
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