Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation

In this study, in situ catalytically generated allylic indium from 1,3 dienes and InCl(2)H was developed for use in the allylation of ketones. This protocol resulted in the unprecedented establishment of a successive combining of quaternary C–C bonds, which could then be applied to many types of ket...

Descripción completa

Detalles Bibliográficos
Autores principales: Suzuki, Itaru, Yagi, Kensuke, Miyamoto, Shinji, Shibata, Ikuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049578/
https://www.ncbi.nlm.nih.gov/pubmed/35497430
http://dx.doi.org/10.1039/d0ra00853b
Descripción
Sumario:In this study, in situ catalytically generated allylic indium from 1,3 dienes and InCl(2)H was developed for use in the allylation of ketones. This protocol resulted in the unprecedented establishment of a successive combining of quaternary C–C bonds, which could then be applied to many types of ketones. Other branched 1,3 dienes and vinyl cyclopropanes, could also be coupled with ketones in a reaction where CuH would not be applicable.

Ejemplares similares