Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation

In this study, in situ catalytically generated allylic indium from 1,3 dienes and InCl(2)H was developed for use in the allylation of ketones. This protocol resulted in the unprecedented establishment of a successive combining of quaternary C–C bonds, which could then be applied to many types of ket...

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Detalles Bibliográficos
Autores principales: Suzuki, Itaru, Yagi, Kensuke, Miyamoto, Shinji, Shibata, Ikuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049578/
https://www.ncbi.nlm.nih.gov/pubmed/35497430
http://dx.doi.org/10.1039/d0ra00853b
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author Suzuki, Itaru
Yagi, Kensuke
Miyamoto, Shinji
Shibata, Ikuya
author_facet Suzuki, Itaru
Yagi, Kensuke
Miyamoto, Shinji
Shibata, Ikuya
author_sort Suzuki, Itaru
collection PubMed
description In this study, in situ catalytically generated allylic indium from 1,3 dienes and InCl(2)H was developed for use in the allylation of ketones. This protocol resulted in the unprecedented establishment of a successive combining of quaternary C–C bonds, which could then be applied to many types of ketones. Other branched 1,3 dienes and vinyl cyclopropanes, could also be coupled with ketones in a reaction where CuH would not be applicable.
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spelling pubmed-90495782022-04-29 Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation Suzuki, Itaru Yagi, Kensuke Miyamoto, Shinji Shibata, Ikuya RSC Adv Chemistry In this study, in situ catalytically generated allylic indium from 1,3 dienes and InCl(2)H was developed for use in the allylation of ketones. This protocol resulted in the unprecedented establishment of a successive combining of quaternary C–C bonds, which could then be applied to many types of ketones. Other branched 1,3 dienes and vinyl cyclopropanes, could also be coupled with ketones in a reaction where CuH would not be applicable. The Royal Society of Chemistry 2020-02-06 /pmc/articles/PMC9049578/ /pubmed/35497430 http://dx.doi.org/10.1039/d0ra00853b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Suzuki, Itaru
Yagi, Kensuke
Miyamoto, Shinji
Shibata, Ikuya
Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation
title Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation
title_full Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation
title_fullStr Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation
title_full_unstemmed Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation
title_short Direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation
title_sort direct use of 1,3-dienes for the allylation of ketones via catalytic hydroindation
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049578/
https://www.ncbi.nlm.nih.gov/pubmed/35497430
http://dx.doi.org/10.1039/d0ra00853b
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