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Uridine inhibits the stemness of intestinal stem cells in 3D intestinal organoids and mice

The activity of intestinal stem cells (ISCs) is foremost in maintaining homeostasis and repair of intestines. As a pivotal substrate of RNA and DNA biosynthesis, uridine plays essential roles in nutritional and disease monitoring. Whether uridine influences ISC activity remains undefined. To answer...

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Detalles Bibliográficos
Autores principales:	Liu, Yi-Lin, Guo, Song-Ge, Xie, Chun-yan, Niu, Kaimin, De Jonge, Hugo, Wu, Xin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society of Chemistry 2020
Materias:	Chemistry
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049648/ https://www.ncbi.nlm.nih.gov/pubmed/35496025 http://dx.doi.org/10.1039/c9ra07742a

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