A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines

A simple synthetic strategy has been developed for the synthesis of 2- and 1-alkyl/aryl/dialkylaminoquinolines and isoquinolines from the easily available quinoline and isoquinoline-N-oxides, different amines, triflic anhydride as activating agent and acetonitrile as solvent in a one-pot reaction un...

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Detalles Bibliográficos
Autores principales: Nanaji, Yerramsetti, Kirar, Seema, Pawar, Sandip V., Yadav, Ashok Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049819/
https://www.ncbi.nlm.nih.gov/pubmed/35492149
http://dx.doi.org/10.1039/c9ra10397j
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author Nanaji, Yerramsetti
Kirar, Seema
Pawar, Sandip V.
Yadav, Ashok Kumar
author_facet Nanaji, Yerramsetti
Kirar, Seema
Pawar, Sandip V.
Yadav, Ashok Kumar
author_sort Nanaji, Yerramsetti
collection PubMed
description A simple synthetic strategy has been developed for the synthesis of 2- and 1-alkyl/aryl/dialkylaminoquinolines and isoquinolines from the easily available quinoline and isoquinoline-N-oxides, different amines, triflic anhydride as activating agent and acetonitrile as solvent in a one-pot reaction under metal-free conditions at 0 °C to room temperature.
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spelling pubmed-90498192022-04-29 A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines Nanaji, Yerramsetti Kirar, Seema Pawar, Sandip V. Yadav, Ashok Kumar RSC Adv Chemistry A simple synthetic strategy has been developed for the synthesis of 2- and 1-alkyl/aryl/dialkylaminoquinolines and isoquinolines from the easily available quinoline and isoquinoline-N-oxides, different amines, triflic anhydride as activating agent and acetonitrile as solvent in a one-pot reaction under metal-free conditions at 0 °C to room temperature. The Royal Society of Chemistry 2020-02-20 /pmc/articles/PMC9049819/ /pubmed/35492149 http://dx.doi.org/10.1039/c9ra10397j Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Nanaji, Yerramsetti
Kirar, Seema
Pawar, Sandip V.
Yadav, Ashok Kumar
A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
title A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
title_full A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
title_fullStr A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
title_full_unstemmed A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
title_short A mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
title_sort mild and metal-free synthesis of 2- and 1-alkyl/aryl/dialkyl-aminoquinolines and isoquinolines
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049819/
https://www.ncbi.nlm.nih.gov/pubmed/35492149
http://dx.doi.org/10.1039/c9ra10397j
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