Palladium-catalysed difluoroolefination of benzyl tosylates toward the synthesis of gem-difluoro-2-trifluromethyl styrene derivatives

We have presented an efficient method to access gem-difluoro-2-trifluromethyl styrene derivatives via palladium catalysis. This method features mild reaction conditions, broad substrate scope and good product yields. Moreover, gram–scale reactions demonstrated the robustness and potential of this me...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Liu, Jiangjun, Chen, Gang, Xiong, Baojian, Zhang, Xuemei, Lian, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2022
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049850/
https://www.ncbi.nlm.nih.gov/pubmed/35497019
http://dx.doi.org/10.1039/d2ra02473j

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