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Genetic loci and metabolic states associated with murine epigenetic aging

Changes in DNA methylation (DNAm) are linked to aging. Here, we profile highly conserved CpGs in 339 predominantly female mice belonging to the BXD family for which we have deep longevity and genomic data. We use a ‘pan-mammalian’ microarray that provides a common platform for assaying the methylome...

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Detalles Bibliográficos
Autores principales:	Mozhui, Khyobeni, Lu, Ake T, Li, Caesar Z, Haghani, Amin, Sandoval-Sierra, Jose Vladimir, Wu, Yibo, Williams, Robert W, Horvath, Steve
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	eLife Sciences Publications, Ltd 2022
Materias:	Chromosomes and Gene Expression
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9049972/ https://www.ncbi.nlm.nih.gov/pubmed/35389339 http://dx.doi.org/10.7554/eLife.75244

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