Cargando…

Downregulated XBP-1 Rescues Cerebral Ischemia/Reperfusion Injury-Induced Pyroptosis via the NLRP3/Caspase-1/GSDMD Axis

Ischemic stroke is a major condition that remains extremely problematic to treat. A cerebral reperfusion injury becomes apparent after an ischemic accident when reoxygenation of the afflicted area produces pathological side effects that are different than those induced by the initial oxygen and nutr...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhang, Yueting, Yao, Zhihui, Xiao, Yan, Zhang, Xiaoling, Liu, Jiaxin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050284/ https://www.ncbi.nlm.nih.gov/pubmed/35497095 http://dx.doi.org/10.1155/2022/8007078

Ejemplares similares

Puerarin protects renal ischemia-reperfusion injury in rats through NLRP3/Caspase-1/GSDMD pathway
por: Wang, Kangyu, et al.
Publicado: (2023)

Metformin protects against intestinal ischemia-reperfusion injury and cell pyroptosis via TXNIP-NLRP3-GSDMD pathway
por: Jia, Yifan, et al.
Publicado: (2020)

GSDMD contributes to myocardial reperfusion injury by regulating pyroptosis
por: Ye, Xiaomiao, et al.
Publicado: (2022)

Cold Stress Induced Liver Injury of Mice through Activated NLRP3/Caspase-1/GSDMD Pyroptosis Signaling Pathway
por: Liu, Yuanyuan, et al.
Publicado: (2022)

Oridonin Protects against Myocardial Ischemia–Reperfusion Injury by Inhibiting GSDMD-Mediated Pyroptosis
por: Lin, Jiahui, et al.
Publicado: (2022)

Hydrogen Sulfide Attenuates Neuroinflammation by Inhibiting the NLRP3/Caspase-1/GSDMD Pathway in Retina or Brain Neuron following Rat Ischemia/Reperfusion
por: Yang, Kun-Li, et al.
Publicado: (2022)

High Glucose Induces the Loss of Retinal Pericytes Partly via NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis
por: Gan, Jinhua, et al.
Publicado: (2020)

Suppression of NLRP3/Caspase-1/GSDMD Mediated Corneal Epithelium Pyroptosis Using Melatonin-Loaded Liposomes to Inhibit Benzalkonium Chloride-Induced Dry Eye Disease
por: Lou, Qi, et al.
Publicado: (2023)

Simvastatin induces pyroptosis via ROS/caspase-1/GSDMD pathway in colon cancer
por: Xie, Wei, et al.
Publicado: (2023)

ERRα promotes glycolytic metabolism and targets the NLRP3/caspase-1/GSDMD pathway to regulate pyroptosis in endometrial cancer
por: Su, Pingping, et al.
Publicado: (2023)

Moxibustion against Cyclophosphamide-Induced Premature Ovarian Failure in Rats through Inhibiting NLRP3-/Caspase-1-/GSDMD-Dependent Pyroptosis
por: Zhang, Cai-rong, et al.
Publicado: (2021)

NLRP3/caspase-1/GSDMD–mediated pyroptosis exerts a crucial role in astrocyte pathological injury in mouse model of depression
por: Li, Shanshan, et al.
Publicado: (2021)

Ophiopogonin B alleviates cisplatin resistance of lung cancer cells by inducing Caspase-1/GSDMD dependent pyroptosis
por: Cheng, Ziyu, et al.
Publicado: (2022)

β-sitosterol alleviates dextran sulfate sodium-induced experimental colitis via inhibition of NLRP3/Caspase-1/GSDMD-mediated pyroptosis
por: Zhang, Di, et al.
Publicado: (2023)

Secoisolariciresinol diglucoside induces pyroptosis by activating caspase‐1 to cleave GSDMD in colorectal cancer cells
por: Chen, Tuo, et al.
Publicado: (2022)

HDAC11 promotes both NLRP3/caspase-1/GSDMD and caspase-3/GSDME pathways causing pyroptosis via ERG in vascular endothelial cells
por: Yao, Feng, et al.
Publicado: (2022)

Cisplatin Induces Pyroptosis via Activation of MEG3/NLRP3/caspase-1/GSDMD Pathway in Triple-Negative Breast Cancer
por: Yan, Honglin, et al.
Publicado: (2021)

Puerarin Inhibits NLRP3-Caspase-1-GSDMD-Mediated Pyroptosis via P2X7 Receptor in Cardiomyocytes and Macrophages
por: Sun, Shuchan, et al.
Publicado: (2023)

Blocking Caspase-1/Gsdmd and Caspase-3/-8/Gsdme pyroptotic pathways rescues silicosis in mice
por: Kang, Lulu, et al.
Publicado: (2022)

Tetracaine hydrochloride induces macrophage pyroptosis through caspase‑1/11‑GSDMD signaling pathways
por: Zhang, Ran, et al.
Publicado: (2023)

STING Induces Liver Ischemia-Reperfusion Injury by Promoting Calcium-Dependent Caspase 1-GSDMD Processing in Macrophages
por: Wu, Xin-yi, et al.
Publicado: (2022)

Ceramide induces pyroptosis through TXNIP/NLRP3/GSDMD pathway in HUVECs
por: Liu, Fangfang, et al.
Publicado: (2022)

Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway
por: Ding, Baozhu, et al.
Publicado: (2021)

Talaromyces marneffei activates the AIM2-caspase-1/-4-GSDMD axis to induce pyroptosis in hepatocytes
por: Wang, Gang, et al.
Publicado: (2022)

Ellagic acid Alleviates hepatic ischemia–reperfusion injury in C57 mice via the Caspase-1-GSDMD pathway
por: Wang, Hao, et al.
Publicado: (2022)

Corrigendum to “Berberine Reduces Renal Cell Pyroptosis in Golden Hamsters with Diabetic Nephropathy through the Nrf2-NLRP3-Caspase-1-GSDMD Pathway”
por: Ding, Baozhu, et al.
Publicado: (2022)

Disulfiram ameliorates ischemia/reperfusion-induced acute kidney injury by suppressing the caspase-11-GSDMD pathway
por: Cai, Qiaoting, et al.
Publicado: (2022)

IP3R1 regulates Ca(2+) transport and pyroptosis through the NLRP3/Caspase-1 pathway in myocardial ischemia/reperfusion injury
por: Mo, Guixi, et al.
Publicado: (2021)

The Inflammasome Drives GSDMD-Independent Secondary Pyroptosis and IL-1 Release in the Absence of Caspase-1 Protease Activity
por: Schneider, Katharina S., et al.
Publicado: (2017)

XBP1 modulates endoplasmic reticulum and mitochondria crosstalk via regulating NLRP3 in renal ischemia/reperfusion injury
por: Ni, Haiqiang, et al.
Publicado: (2023)

Mechanism of Electroacupuncture Against Cerebral Ischemia–Reperfusion Injury: Reducing Inflammatory Response and Cell Pyroptosis by Inhibiting NLRP3 and Caspase-1
por: Cai, Li, et al.
Publicado: (2022)

Calcitriol Alleviates Hyperosmotic Stress-Induced Corneal Epithelial Cell Damage via Inhibiting the NLRP3–ASC–Caspase-1–GSDMD Pyroptosis Pathway in Dry Eye Disease
por: Zhang, Jing, et al.
Publicado: (2021)

SIRT1 alleviates hepatic ischemia-reperfusion injury via the miR-182-mediated XBP1/NLRP3 pathway
por: Li, Fengwei, et al.
Publicado: (2020)

Didymin Suppresses Microglia Pyroptosis and Neuroinflammation Through the Asc/Caspase-1/GSDMD Pathway Following Experimental Intracerebral Hemorrhage
por: Gu, Lingui, et al.
Publicado: (2022)

Downregulation of XBP1 protects kidney against ischemia-reperfusion injury via suppressing HRD1-mediated NRF2 ubiquitylation
por: Zhang, Ji, et al.
Publicado: (2021)

Polyphyllin VI Induces Caspase-1-Mediated Pyroptosis via the Induction of ROS/NF-κB/NLRP3/GSDMD Signal Axis in Non-Small Cell Lung Cancer
por: Teng, Jin-Feng, et al.
Publicado: (2020)

Emodin Alleviates High-Glucose-Induced Pancreatic β-Cell Pyroptosis by Inhibiting NLRP3/GSDMD Signaling
por: Xing, Yiqian, et al.
Publicado: (2022)

Tisp40 Induces Tubular Epithelial Cell GSDMD-Mediated Pyroptosis in Renal Ischemia-Reperfusion Injury via NF-κB Signaling
por: Xiao, Chengcheng, et al.
Publicado: (2020)

Trimetazidine attenuates dexamethasone-induced muscle atrophy via inhibiting NLRP3/GSDMD pathway-mediated pyroptosis
por: Wang, Li, et al.
Publicado: (2021)

Myoglobin promotes macrophage polarization to M1 type and pyroptosis via the RIG-I/Caspase1/GSDMD signaling pathway in CS-AKI
por: Li, Ning, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_679e1as464po8rrrhe1gv1cg9g