Solvent-free and room temperature microwave-assisted direct C7 allylation of indolines via sequential C–H and C–C activation

A Ru or Rh-catalyzed efficient and atom-economic C7 allylation of indolines with vinylcyclopropanes was developed via sequential C–H and C–C activation. A wide range of substrates were well tolerated to afford the corresponding allylated indolines in high yields and E/Z selectivities under microwave...

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Autores principales: Wang, Qiuling, Shi, Linlin, Liu, Shuang, Zhi, Changlei, Fu, Lian-Rong, Zhu, Xinju, Hao, Xin-Qi, Song, Mao-Ping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050424/
https://www.ncbi.nlm.nih.gov/pubmed/35492909
http://dx.doi.org/10.1039/d0ra02016h
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author Wang, Qiuling
Shi, Linlin
Liu, Shuang
Zhi, Changlei
Fu, Lian-Rong
Zhu, Xinju
Hao, Xin-Qi
Song, Mao-Ping
author_facet Wang, Qiuling
Shi, Linlin
Liu, Shuang
Zhi, Changlei
Fu, Lian-Rong
Zhu, Xinju
Hao, Xin-Qi
Song, Mao-Ping
author_sort Wang, Qiuling
collection PubMed
description A Ru or Rh-catalyzed efficient and atom-economic C7 allylation of indolines with vinylcyclopropanes was developed via sequential C–H and C–C activation. A wide range of substrates were well tolerated to afford the corresponding allylated indolines in high yields and E/Z selectivities under microwave irradiation. The obtained allylated indolines could further undergo transformations to afford various value-added chemicals. Importantly, this reaction proceeded at room temperature under solvent-free conditions.
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spelling pubmed-90504242022-04-29 Solvent-free and room temperature microwave-assisted direct C7 allylation of indolines via sequential C–H and C–C activation Wang, Qiuling Shi, Linlin Liu, Shuang Zhi, Changlei Fu, Lian-Rong Zhu, Xinju Hao, Xin-Qi Song, Mao-Ping RSC Adv Chemistry A Ru or Rh-catalyzed efficient and atom-economic C7 allylation of indolines with vinylcyclopropanes was developed via sequential C–H and C–C activation. A wide range of substrates were well tolerated to afford the corresponding allylated indolines in high yields and E/Z selectivities under microwave irradiation. The obtained allylated indolines could further undergo transformations to afford various value-added chemicals. Importantly, this reaction proceeded at room temperature under solvent-free conditions. The Royal Society of Chemistry 2020-03-17 /pmc/articles/PMC9050424/ /pubmed/35492909 http://dx.doi.org/10.1039/d0ra02016h Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Wang, Qiuling
Shi, Linlin
Liu, Shuang
Zhi, Changlei
Fu, Lian-Rong
Zhu, Xinju
Hao, Xin-Qi
Song, Mao-Ping
Solvent-free and room temperature microwave-assisted direct C7 allylation of indolines via sequential C–H and C–C activation
title Solvent-free and room temperature microwave-assisted direct C7 allylation of indolines via sequential C–H and C–C activation
title_full Solvent-free and room temperature microwave-assisted direct C7 allylation of indolines via sequential C–H and C–C activation
title_fullStr Solvent-free and room temperature microwave-assisted direct C7 allylation of indolines via sequential C–H and C–C activation
title_full_unstemmed Solvent-free and room temperature microwave-assisted direct C7 allylation of indolines via sequential C–H and C–C activation
title_short Solvent-free and room temperature microwave-assisted direct C7 allylation of indolines via sequential C–H and C–C activation
title_sort solvent-free and room temperature microwave-assisted direct c7 allylation of indolines via sequential c–h and c–c activation
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050424/
https://www.ncbi.nlm.nih.gov/pubmed/35492909
http://dx.doi.org/10.1039/d0ra02016h
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