Alumina-promoted oxodefluorination

A simple protocol for the clean preparation of heterocyclic compounds containing dibenzofuran's core via oxodefluorination of fluoroarenes on activated γ-Al(2)O(3) is reported. Alumina can be considered as a reliable oxygen source enabling one-pot substitution of fluorine atoms and yielding ben...

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Detalles Bibliográficos
Autores principales: Vladimir, Akhmetov, Mikhail, Feofanov, Amsharov, Konstantin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050430/
https://www.ncbi.nlm.nih.gov/pubmed/35492952
http://dx.doi.org/10.1039/d0ra01369b
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author Vladimir, Akhmetov
Mikhail, Feofanov
Amsharov, Konstantin
author_facet Vladimir, Akhmetov
Mikhail, Feofanov
Amsharov, Konstantin
author_sort Vladimir, Akhmetov
collection PubMed
description A simple protocol for the clean preparation of heterocyclic compounds containing dibenzofuran's core via oxodefluorination of fluoroarenes on activated γ-Al(2)O(3) is reported. Alumina can be considered as a reliable oxygen source enabling one-pot substitution of fluorine atoms and yielding benzoannulated furan derivatives. The corresponding C–F bond activation is selective towards less stable C–Br/C–I and occurs under metal- and solvent-free conditions.
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spelling pubmed-90504302022-04-29 Alumina-promoted oxodefluorination Vladimir, Akhmetov Mikhail, Feofanov Amsharov, Konstantin RSC Adv Chemistry A simple protocol for the clean preparation of heterocyclic compounds containing dibenzofuran's core via oxodefluorination of fluoroarenes on activated γ-Al(2)O(3) is reported. Alumina can be considered as a reliable oxygen source enabling one-pot substitution of fluorine atoms and yielding benzoannulated furan derivatives. The corresponding C–F bond activation is selective towards less stable C–Br/C–I and occurs under metal- and solvent-free conditions. The Royal Society of Chemistry 2020-03-17 /pmc/articles/PMC9050430/ /pubmed/35492952 http://dx.doi.org/10.1039/d0ra01369b Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/
spellingShingle Chemistry
Vladimir, Akhmetov
Mikhail, Feofanov
Amsharov, Konstantin
Alumina-promoted oxodefluorination
title Alumina-promoted oxodefluorination
title_full Alumina-promoted oxodefluorination
title_fullStr Alumina-promoted oxodefluorination
title_full_unstemmed Alumina-promoted oxodefluorination
title_short Alumina-promoted oxodefluorination
title_sort alumina-promoted oxodefluorination
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050430/
https://www.ncbi.nlm.nih.gov/pubmed/35492952
http://dx.doi.org/10.1039/d0ra01369b
work_keys_str_mv AT vladimirakhmetov aluminapromotedoxodefluorination
AT mikhailfeofanov aluminapromotedoxodefluorination
AT amsharovkonstantin aluminapromotedoxodefluorination

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