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Access to N-unprotected 2-amide-substituted indoles from Ugi adducts via palladium-catalyzed intramolecular cyclization of o-iodoanilines bearing furan rings

A variety of N-unprotected 2-amide-substituted indoles were synthesized from readily available furfural-based Ugi adducts in moderate to good yields via palladium-catalyzed intramolecular cyclization of o-iodoanilines bearing furan rings. These reactions involved a cascade sequence consisting of dea...

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Detalles Bibliográficos
Autores principales: Peng, Hui, Jiang, Kai, Zhen, Guangjin, Wang, Furong, Yin, Biaolin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050509/
https://www.ncbi.nlm.nih.gov/pubmed/35496608
http://dx.doi.org/10.1039/d0ra01830a