Single-cell sequencing of human midbrain reveals glial activation and a Parkinson-specific neuronal state

Idiopathic Parkinson’s disease is characterized by a progressive loss of dopaminergic neurons, but the exact disease aetiology remains largely unknown. To date, Parkinson’s disease research has mainly focused on nigral dopaminergic neurons, although recent studies suggest disease-related changes als...

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Detalles Bibliográficos
Autores principales: Smajić, Semra, Prada-Medina, Cesar A., Landoulsi, Zied, Ghelfi, Jenny, Delcambre, Sylvie, Dietrich, Carola, Jarazo, Javier, Henck, Jana, Balachandran, Saranya, Pachchek, Sinthuja, Morris, Christopher M., Antony, Paul, Timmermann, Bernd, Sauer, Sascha, Pereira, Sandro L., Schwamborn, Jens C., May, Patrick, Grünewald, Anne, Spielmann, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2021
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050543/
https://www.ncbi.nlm.nih.gov/pubmed/34919646
http://dx.doi.org/10.1093/brain/awab446

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