Delta spike P681R mutation enhances SARS-CoV-2 fitness over Alpha variant

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We report that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) Delta spike mutation P681R plays a key role in the Alpha-to-Delta variant replacement during the coronavirus disease 2019 (COVID-19) pandemic. Delta SARS-CoV-2 efficiently outcompetes the Alpha variant in human lung epitheli...

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Detalles Bibliográficos
Autores principales: Liu, Yang, Liu, Jianying, Johnson, Bryan A., Xia, Hongjie, Ku, Zhiqiang, Schindewolf, Craig, Widen, Steven G., An, Zhiqiang, Weaver, Scott C., Menachery, Vineet D., Xie, Xuping, Shi, Pei-Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Authors. 2022
Materias:
Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050581/
https://www.ncbi.nlm.nih.gov/pubmed/35550680
http://dx.doi.org/10.1016/j.celrep.2022.110829
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