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Mg(3)N(2)-assisted one-pot synthesis of 1,3-disubstituted imidazo[1,5-a]pyridine

A novel Mg(3)N(2)-assisted one-pot annulation strategy has been developed via cyclo-condensation reaction of 2-pyridyl ketones with alkyl glyoxylates or aldehydes, allowing the formation of imidazo[1,5-a]pyridines exclusively with an exellent yield.

Detalles Bibliográficos
Autores principales: Patil, Suhas G., Jadhav, Jagannath S., Sankpal, Sagar T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050600/
https://www.ncbi.nlm.nih.gov/pubmed/35496590
http://dx.doi.org/10.1039/c9ra10848c
Descripción
Sumario:A novel Mg(3)N(2)-assisted one-pot annulation strategy has been developed via cyclo-condensation reaction of 2-pyridyl ketones with alkyl glyoxylates or aldehydes, allowing the formation of imidazo[1,5-a]pyridines exclusively with an exellent yield.