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Mg(3)N(2)-assisted one-pot synthesis of 1,3-disubstituted imidazo[1,5-a]pyridine
A novel Mg(3)N(2)-assisted one-pot annulation strategy has been developed via cyclo-condensation reaction of 2-pyridyl ketones with alkyl glyoxylates or aldehydes, allowing the formation of imidazo[1,5-a]pyridines exclusively with an exellent yield.
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050600/ https://www.ncbi.nlm.nih.gov/pubmed/35496590 http://dx.doi.org/10.1039/c9ra10848c |
Sumario: | A novel Mg(3)N(2)-assisted one-pot annulation strategy has been developed via cyclo-condensation reaction of 2-pyridyl ketones with alkyl glyoxylates or aldehydes, allowing the formation of imidazo[1,5-a]pyridines exclusively with an exellent yield. |
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