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OVOL1 inhibits breast cancer cell invasion by enhancing the degradation of TGF-β type I receptor

Ovo-like transcriptional repressor 1 (OVOL1) is a key mediator of epithelial lineage determination and mesenchymal–epithelial transition (MET). The cytokines transforming growth factor-β (TGF-β) and bone morphogenetic proteins (BMP) control the epithelial–mesenchymal plasticity (EMP) of cancer cells...

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Detalles Bibliográficos
Autores principales: Fan, Chuannan, Wang, Qian, van der Zon, Gerard, Ren, Jiang, Agaser, Cedrick, Slieker, Roderick C., Iyengar, Prasanna Vasudevan, Mei, Hailiang, ten Dijke, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050647/
https://www.ncbi.nlm.nih.gov/pubmed/35484112
http://dx.doi.org/10.1038/s41392-022-00944-w