Nucleosome footprinting in plasma cell-free DNA for the pre-surgical diagnosis of ovarian cancer

Fragmentation patterns of plasma cell-free DNA (cfDNA) are known to reflect nucleosome positions of cell types contributing to cfDNA. Based on cfDNA fragmentation patterns, the deviation in nucleosome footprints was quantified between diagnosed ovarian cancer patients and healthy individuals. Multin...

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Detalles Bibliográficos
Autores principales: Vanderstichele, Adriaan, Busschaert, Pieter, Landolfo, Chiara, Olbrecht, Siel, Coosemans, An, Froyman, Wouter, Loverix, Liselore, Concin, Nicole, Braicu, Elena Ioana, Wimberger, Pauline, Van Nieuwenhuysen, Els, Han, Sileny N., Van Gorp, Toon, Venken, Tom, Heremans, Ruben, Neven, Patrick, Bourne, Tom, Van Calster, Ben, Timmerman, Dirk, Lambrechts, Diether, Vergote, Ignace
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050708/
https://www.ncbi.nlm.nih.gov/pubmed/35484288
http://dx.doi.org/10.1038/s41525-022-00300-5

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