Somatic whole genome dynamics of precancer in Barrett’s esophagus reveals features associated with disease progression

While the genomes of normal tissues undergo dynamic changes over time, little is understood about the temporal-spatial dynamics of genomes in premalignant tissues that progress to cancer compared to those that remain cancer-free. Here we use whole genome sequencing to contrast genomic alterations in...

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Detalles Bibliográficos
Autores principales: Paulson, Thomas G., Galipeau, Patricia C., Oman, Kenji M., Sanchez, Carissa A., Kuhner, Mary K., Smith, Lucian P., Hadi, Kevin, Shah, Minita, Arora, Kanika, Shelton, Jennifer, Johnson, Molly, Corvelo, Andre, Maley, Carlo C., Yao, Xiaotong, Sanghvi, Rashesh, Venturini, Elisa, Emde, Anne-Katrin, Hubert, Benjamin, Imielinski, Marcin, Robine, Nicolas, Reid, Brian J., Li, Xiaohong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050715/
https://www.ncbi.nlm.nih.gov/pubmed/35484108
http://dx.doi.org/10.1038/s41467-022-29767-7

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