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Kidney epithelial cells are active mechano-biological fluid pumps
The role of mechanical forces driving kidney epithelial fluid transport and morphogenesis in kidney diseases is unclear. Here, using a microfluidic platform to recapitulate fluid transport activity of kidney cells, we report that renal epithelial cells can actively generate hydraulic pressure gradie...
Autores principales: | Choudhury, Mohammad Ikbal, Li, Yizeng, Mistriotis, Panagiotis, Vasconcelos, Ana Carina N., Dixon, Eryn E., Yang, Jing, Benson, Morgan, Maity, Debonil, Walker, Rebecca, Martin, Leigha, Koroma, Fatima, Qian, Feng, Konstantopoulos, Konstantinos, Woodward, Owen M., Sun, Sean X. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050750/ https://www.ncbi.nlm.nih.gov/pubmed/35484146 http://dx.doi.org/10.1038/s41467-022-29988-w |
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