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Population Pharmacokinetic Model for Tramadol and O-desmethyltramadol in Older Patients
BACKGROUND AND OBJECTIVES: Tramadol is commonly prescribed to manage chronic pain in older patients. However, there is a gap in the literature describing the pharmacokinetic parameters for tramadol and its active metabolite (O-desmethyltramadol [ODT]) in this population. The objective of this study...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050769/ https://www.ncbi.nlm.nih.gov/pubmed/35167052 http://dx.doi.org/10.1007/s13318-022-00756-x |