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Population Pharmacokinetic Model for Tramadol and O-desmethyltramadol in Older Patients

BACKGROUND AND OBJECTIVES: Tramadol is commonly prescribed to manage chronic pain in older patients. However, there is a gap in the literature describing the pharmacokinetic parameters for tramadol and its active metabolite (O-desmethyltramadol [ODT]) in this population. The objective of this study...

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Detalles Bibliográficos
Autores principales: Al-Qurain, Aymen A., Upton, Richard N., Tadros, Rami, Roberts, Michael S., Wiese, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050769/
https://www.ncbi.nlm.nih.gov/pubmed/35167052
http://dx.doi.org/10.1007/s13318-022-00756-x