Altered propionate metabolism contributes to tumor progression and aggressiveness

The alteration of metabolic pathways is a critical strategy for cancer cells to attain the traits necessary for metastasis in disease progression. Here, we find that dysregulation of propionate metabolism produces a pro-aggressive signature in breast and lung cancer cells, increasing their metastati...

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Detalles Bibliográficos
Autores principales: Gomes, Ana P., Ilter, Didem, Low, Vivien, Drapela, Stanislav, Schild, Tanya, Mullarky, Edouard, Han, Julie, Elia, Ilaria, Broekaert, Dorien, Rosenzweig, Adam, Nagiec, Michal, Nunes, Joana B., Schaffer, Bethany E., Mutvei, Anders P., Asara, John M., Cantley, Lewis C., Fendt, Sarah-Maria, Blenis, John
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050834/
https://www.ncbi.nlm.nih.gov/pubmed/35361954
http://dx.doi.org/10.1038/s42255-022-00553-5

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