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Concurrent delivery of immune checkpoint blockade modulates T cell dynamics to enhance neoantigen vaccine-generated anti-tumor immunity

Neoantigen vaccines aiming to induce tumor-specific T cell responses have achieved promising anti-tumor effects in early clinical trials. However, the underlying mechanism regarding response or resistance to this treatment remains unclear. Here, we observe that neoantigen vaccine-generated T cells c...

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Detalles Bibliográficos
Autores principales:	Liu, Longchao, Chen, Jiahui, Zhang, Hongyi, Ye, Jianfeng, Moore, Casey, Lu, Changzheng, Fang, Yan, Fu, Yang-Xin, Li, Bo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050907/ https://www.ncbi.nlm.nih.gov/pubmed/35393580 http://dx.doi.org/10.1038/s43018-022-00352-7

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