Cargando…

Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy

BACKGROUND: Radiofrequency ablation (RFA) is a minimally invasive technique used for the treatment of neoplasms, with a growing interest in the treatment of bone tumours. However, the lack of data concerning the size of the resulting ablation zones in RFA of bone tumours makes prospective planning c...

Descripción completa

Detalles Bibliográficos
Autores principales: Rivas Loya, Ricardo, Jutte, Paul C., Kwee, Thomas C., van Ooijen, Peter M. A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Vienna 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050991/
https://www.ncbi.nlm.nih.gov/pubmed/35482168
http://dx.doi.org/10.1186/s41747-022-00271-3
_version_ 1784696463906832384
author Rivas Loya, Ricardo
Jutte, Paul C.
Kwee, Thomas C.
van Ooijen, Peter M. A.
author_facet Rivas Loya, Ricardo
Jutte, Paul C.
Kwee, Thomas C.
van Ooijen, Peter M. A.
author_sort Rivas Loya, Ricardo
collection PubMed
description BACKGROUND: Radiofrequency ablation (RFA) is a minimally invasive technique used for the treatment of neoplasms, with a growing interest in the treatment of bone tumours. However, the lack of data concerning the size of the resulting ablation zones in RFA of bone tumours makes prospective planning challenging, needed for safe and effective treatment. METHODS: Using retrospective computed tomography and magnetic resonance imaging data from patients treated with RFA of atypical cartilaginous tumours (ACTs), the bone, tumours, and final position of the RFA electrode were segmented from the medical images and used in finite element models to simulate RFA. Tissue parameters were optimised, and boundary conditions were defined to mimic the clinical scenario. The resulting ablation diameters from postoperative images were then measured and compared to the ones from the simulations, and the error between them was calculated. RESULTS: Seven cases had all the information required to create the finite element models. The resulting median error (in all three directions) was -1 mm, with interquartile ranges from -3 to 3 mm. The three-dimensional models showed that the thermal damage concentrates close to the cortical wall in the first minutes and then becomes more evenly distributed. CONCLUSIONS: Computer simulations can predict the ablation diameters with acceptable accuracy and may thus be utilised for patient planning. This could allow interventional radiologists to accurately define the time, electrode length, and position required to treat ACTs with RFA and make adjustments as needed to guarantee total tumour destruction while sparing as much healthy tissue as possible.
format Online
Article
Text
id pubmed-9050991
institution National Center for Biotechnology Information
language English
publishDate 2022
publisher Springer Vienna
record_format MEDLINE/PubMed
spelling pubmed-90509912022-05-07 Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy Rivas Loya, Ricardo Jutte, Paul C. Kwee, Thomas C. van Ooijen, Peter M. A. Eur Radiol Exp Original Article BACKGROUND: Radiofrequency ablation (RFA) is a minimally invasive technique used for the treatment of neoplasms, with a growing interest in the treatment of bone tumours. However, the lack of data concerning the size of the resulting ablation zones in RFA of bone tumours makes prospective planning challenging, needed for safe and effective treatment. METHODS: Using retrospective computed tomography and magnetic resonance imaging data from patients treated with RFA of atypical cartilaginous tumours (ACTs), the bone, tumours, and final position of the RFA electrode were segmented from the medical images and used in finite element models to simulate RFA. Tissue parameters were optimised, and boundary conditions were defined to mimic the clinical scenario. The resulting ablation diameters from postoperative images were then measured and compared to the ones from the simulations, and the error between them was calculated. RESULTS: Seven cases had all the information required to create the finite element models. The resulting median error (in all three directions) was -1 mm, with interquartile ranges from -3 to 3 mm. The three-dimensional models showed that the thermal damage concentrates close to the cortical wall in the first minutes and then becomes more evenly distributed. CONCLUSIONS: Computer simulations can predict the ablation diameters with acceptable accuracy and may thus be utilised for patient planning. This could allow interventional radiologists to accurately define the time, electrode length, and position required to treat ACTs with RFA and make adjustments as needed to guarantee total tumour destruction while sparing as much healthy tissue as possible. Springer Vienna 2022-04-28 /pmc/articles/PMC9050991/ /pubmed/35482168 http://dx.doi.org/10.1186/s41747-022-00271-3 Text en © The Author(s) under exclusive licence to European Society of Radiology 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Rivas Loya, Ricardo
Jutte, Paul C.
Kwee, Thomas C.
van Ooijen, Peter M. A.
Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy
title Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy
title_full Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy
title_fullStr Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy
title_full_unstemmed Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy
title_short Computer 3D modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy
title_sort computer 3d modeling of radiofrequency ablation of atypical cartilaginous tumours in long bones using finite element methods and real patient anatomy
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9050991/
https://www.ncbi.nlm.nih.gov/pubmed/35482168
http://dx.doi.org/10.1186/s41747-022-00271-3
work_keys_str_mv AT rivasloyaricardo computer3dmodelingofradiofrequencyablationofatypicalcartilaginoustumoursinlongbonesusingfiniteelementmethodsandrealpatientanatomy
AT juttepaulc computer3dmodelingofradiofrequencyablationofatypicalcartilaginoustumoursinlongbonesusingfiniteelementmethodsandrealpatientanatomy
AT kweethomasc computer3dmodelingofradiofrequencyablationofatypicalcartilaginoustumoursinlongbonesusingfiniteelementmethodsandrealpatientanatomy
AT vanooijenpeterma computer3dmodelingofradiofrequencyablationofatypicalcartilaginoustumoursinlongbonesusingfiniteelementmethodsandrealpatientanatomy