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Protective effects of a SIRT1 inhibitor on primordial follicle activation and growth induced by cyclophosphamide: insights from a bovine in vitro folliculogenesis system

PURPOSE: Although oncological advances have improved survival rates of female cancer patients, they often suffer a reduced fertility due to treatment side effects. In the present study, we evaluated the potential fertoprotective effects of the specific inhibitor of SIRT1, EX-527, on the gonadotoxic...

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Detalles Bibliográficos
Autores principales:	Di Emidio, Giovanna, Tatone, Carla, Barbato, Vincenza, Genovese, Vincenzo, Placidi, Martina, Talevi, Riccardo, Gualtieri, Roberto
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer US 2022
Materias:	Reproductive Physiology and Disease
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051010/ https://www.ncbi.nlm.nih.gov/pubmed/35247119 http://dx.doi.org/10.1007/s10815-022-02437-9

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