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A systems genomics approach to uncover patient-specific pathogenic pathways and proteins in ulcerative colitis

We describe a precision medicine workflow, the integrated single nucleotide polymorphism network platform (iSNP), designed to determine the mechanisms by which SNPs affect cellular regulatory networks, and how SNP co-occurrences contribute to disease pathogenesis in ulcerative colitis (UC). Using SN...

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Detalles Bibliográficos
Autores principales:	Brooks-Warburton, Johanne, Modos, Dezso, Sudhakar, Padhmanand, Madgwick, Matthew, Thomas, John P., Bohar, Balazs, Fazekas, David, Zoufir, Azedine, Kapuy, Orsolya, Szalay-Beko, Mate, Verstockt, Bram, Hall, Lindsay J., Watson, Alastair, Tremelling, Mark, Parkes, Miles, Vermeire, Severine, Bender, Andreas, Carding, Simon R., Korcsmaros, Tamas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051123/ https://www.ncbi.nlm.nih.gov/pubmed/35484353 http://dx.doi.org/10.1038/s41467-022-29998-8

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