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Hyperthermia and Heat Stress as Risk Factors for Sudden Infant Death Syndrome: A Narrative Review

BACKGROUND AND OBJECTIVES: Heat stress and hyperthermia are common findings in sudden infant death syndrome (SIDS) victims. It has been suggested that thermal stress can increase the risk of SIDS directly via lethal hyperthermia or indirectly by altering autonomic functions. Major changes in sleep,...

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Autores principales: Bach, Véronique, Libert, Jean-Pierre
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051231/
https://www.ncbi.nlm.nih.gov/pubmed/35498814
http://dx.doi.org/10.3389/fped.2022.816136
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author Bach, Véronique
Libert, Jean-Pierre
author_facet Bach, Véronique
Libert, Jean-Pierre
author_sort Bach, Véronique
collection PubMed
description BACKGROUND AND OBJECTIVES: Heat stress and hyperthermia are common findings in sudden infant death syndrome (SIDS) victims. It has been suggested that thermal stress can increase the risk of SIDS directly via lethal hyperthermia or indirectly by altering autonomic functions. Major changes in sleep, thermoregulation, cardiovascular function, and the emergence of circadian functions occur at the age at which the risk of SIDS peaks—explaining the greater vulnerability at this stage of development. Here, we review the literature data on (i) heat stress and hyperthermia as direct risk factors for SIDS, and (ii) the indirect effects of thermal loads on vital physiological functions. RESULTS: Various situations leading to thermal stress (i.e., outdoors temperatures, thermal insulation from clothing and bedding, the prone position, bed-sharing, and head covering) have been analyzed. Hyperthermia mainly results from excessive clothing and bedding insulation with regard to the ambient thermal conditions. The appropriate amount of clothing and bedding thermal insulation for homeothermia requires further research. The prone position and bed-sharing do not have major thermal impacts; the elevated risk of SIDS in these situations cannot be explained solely by thermal factors. Special attention should be given to brain overheating because of the head's major role in body heat losses, heat production, and autonomic functions. Thermal stress can alter cardiovascular and respiratory functions, which in turn can lead to life-threatening events (e.g., bradycardia, apnea with blood desaturation, and glottal closure). Unfortunately, thermal load impairs the responses to these challenges by reducing chemosensitivity, arousability, and autoresuscitation. As a result, thermal load (even when not lethal directly) can interact detrimentally with vital physiological functions. CONCLUSIONS: With the exception of excessive thermal insulation (which can lead to lethal hyperthermia), the major risk factors for SIDS appears to be associated with impairments of vital physiological functions when the infant is exposed to thermal stress.
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spelling pubmed-90512312022-04-30 Hyperthermia and Heat Stress as Risk Factors for Sudden Infant Death Syndrome: A Narrative Review Bach, Véronique Libert, Jean-Pierre Front Pediatr Pediatrics BACKGROUND AND OBJECTIVES: Heat stress and hyperthermia are common findings in sudden infant death syndrome (SIDS) victims. It has been suggested that thermal stress can increase the risk of SIDS directly via lethal hyperthermia or indirectly by altering autonomic functions. Major changes in sleep, thermoregulation, cardiovascular function, and the emergence of circadian functions occur at the age at which the risk of SIDS peaks—explaining the greater vulnerability at this stage of development. Here, we review the literature data on (i) heat stress and hyperthermia as direct risk factors for SIDS, and (ii) the indirect effects of thermal loads on vital physiological functions. RESULTS: Various situations leading to thermal stress (i.e., outdoors temperatures, thermal insulation from clothing and bedding, the prone position, bed-sharing, and head covering) have been analyzed. Hyperthermia mainly results from excessive clothing and bedding insulation with regard to the ambient thermal conditions. The appropriate amount of clothing and bedding thermal insulation for homeothermia requires further research. The prone position and bed-sharing do not have major thermal impacts; the elevated risk of SIDS in these situations cannot be explained solely by thermal factors. Special attention should be given to brain overheating because of the head's major role in body heat losses, heat production, and autonomic functions. Thermal stress can alter cardiovascular and respiratory functions, which in turn can lead to life-threatening events (e.g., bradycardia, apnea with blood desaturation, and glottal closure). Unfortunately, thermal load impairs the responses to these challenges by reducing chemosensitivity, arousability, and autoresuscitation. As a result, thermal load (even when not lethal directly) can interact detrimentally with vital physiological functions. CONCLUSIONS: With the exception of excessive thermal insulation (which can lead to lethal hyperthermia), the major risk factors for SIDS appears to be associated with impairments of vital physiological functions when the infant is exposed to thermal stress. Frontiers Media S.A. 2022-04-15 /pmc/articles/PMC9051231/ /pubmed/35498814 http://dx.doi.org/10.3389/fped.2022.816136 Text en Copyright © 2022 Bach and Libert. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pediatrics
Bach, Véronique
Libert, Jean-Pierre
Hyperthermia and Heat Stress as Risk Factors for Sudden Infant Death Syndrome: A Narrative Review
title Hyperthermia and Heat Stress as Risk Factors for Sudden Infant Death Syndrome: A Narrative Review
title_full Hyperthermia and Heat Stress as Risk Factors for Sudden Infant Death Syndrome: A Narrative Review
title_fullStr Hyperthermia and Heat Stress as Risk Factors for Sudden Infant Death Syndrome: A Narrative Review
title_full_unstemmed Hyperthermia and Heat Stress as Risk Factors for Sudden Infant Death Syndrome: A Narrative Review
title_short Hyperthermia and Heat Stress as Risk Factors for Sudden Infant Death Syndrome: A Narrative Review
title_sort hyperthermia and heat stress as risk factors for sudden infant death syndrome: a narrative review
topic Pediatrics
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051231/
https://www.ncbi.nlm.nih.gov/pubmed/35498814
http://dx.doi.org/10.3389/fped.2022.816136
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