Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols

A coumarin-based novel ‘AND’ logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO(−) and biological thiols. ROS-AHC was shown to exhibit only a very small fluorescence response upon addition of a single GSH or ONOO(−) analyte. Exposure to both analytes, however,...

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Detalles Bibliográficos
Autores principales: Wu, Luling, Tian, Xue, Groleau, Robin R., Wang, Jie, Han, Hai-Hao, Reeksting, Shaun B., Sedgwick, Adam C., He, Xiao-Peng, Bull, Steven D., James, Tony D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Royal Society of Chemistry 2020
Materias:
Chemistry
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051425/
https://www.ncbi.nlm.nih.gov/pubmed/35493005
http://dx.doi.org/10.1039/d0ra02234a
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author Wu, Luling
Tian, Xue
Groleau, Robin R.
Wang, Jie
Han, Hai-Hao
Reeksting, Shaun B.
Sedgwick, Adam C.
He, Xiao-Peng
Bull, Steven D.
James, Tony D.
author_facet Wu, Luling
Tian, Xue
Groleau, Robin R.
Wang, Jie
Han, Hai-Hao
Reeksting, Shaun B.
Sedgwick, Adam C.
He, Xiao-Peng
Bull, Steven D.
James, Tony D.
author_sort Wu, Luling
collection PubMed
description A coumarin-based novel ‘AND’ logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO(−) and biological thiols. ROS-AHC was shown to exhibit only a very small fluorescence response upon addition of a single GSH or ONOO(−) analyte. Exposure to both analytes, however, resulted in a significant fluorescence enhancement.
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spelling pubmed-90514252022-04-29 Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols Wu, Luling Tian, Xue Groleau, Robin R. Wang, Jie Han, Hai-Hao Reeksting, Shaun B. Sedgwick, Adam C. He, Xiao-Peng Bull, Steven D. James, Tony D. RSC Adv Chemistry A coumarin-based novel ‘AND’ logic fluorescent probe ROS-AHC has been developed for the simultaneous detection of ONOO(−) and biological thiols. ROS-AHC was shown to exhibit only a very small fluorescence response upon addition of a single GSH or ONOO(−) analyte. Exposure to both analytes, however, resulted in a significant fluorescence enhancement. The Royal Society of Chemistry 2020-04-03 /pmc/articles/PMC9051425/ /pubmed/35493005 http://dx.doi.org/10.1039/d0ra02234a Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by/3.0/
spellingShingle Chemistry
Wu, Luling
Tian, Xue
Groleau, Robin R.
Wang, Jie
Han, Hai-Hao
Reeksting, Shaun B.
Sedgwick, Adam C.
He, Xiao-Peng
Bull, Steven D.
James, Tony D.
Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols
title Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols
title_full Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols
title_fullStr Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols
title_full_unstemmed Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols
title_short Coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘AND’ biological thiols
title_sort coumarin-based fluorescent probe for the rapid detection of peroxynitrite ‘and’ biological thiols
topic Chemistry
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051425/
https://www.ncbi.nlm.nih.gov/pubmed/35493005
http://dx.doi.org/10.1039/d0ra02234a
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