Phosphate-regulated expression of the SARS-CoV-2 receptor-binding domain in the diatom Phaeodactylum tricornutum for pandemic diagnostics

The worldwide COVID-19 pandemic caused by the SARS-CoV-2 betacoronavirus has highlighted the need for a synthetic biology approach to create reliable and scalable sources of viral antigen for uses in diagnostics, therapeutics and basic biomedical research. Here, we adapt plasmid-based systems in the...

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Detalles Bibliográficos
Autores principales: Slattery, Samuel S., Giguere, Daniel J., Stuckless, Emily E., Shrestha, Arina, Briere, Lee-Ann K., Galbraith, Alexa, Reaume, Stephen, Boyko, Xenia, Say, Henry H., Browne, Tyler S., Frederick, Mallory I., Lant, Jeremy T., Heinemann, Ilka U., O’Donoghue, Patrick, Dsouza, Liann, Martin, Steven, Howard, Peter, Jedeszko, Christopher, Ali, Kinza, Styba, Garth, Flatley, Martin, Karas, Bogumil J., Gloor, Gregory B., Edgell, David R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051505/
https://www.ncbi.nlm.nih.gov/pubmed/35487958
http://dx.doi.org/10.1038/s41598-022-11053-7

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