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Measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (PRISM)
INTRODUCTION: Although the Food and Drug Administration banned other characterising flavours in cigarettes, menthol cigarettes are still available to consumers. Young adult new smokers are initiating with menthol cigarettes, such that the prevalence of young adults menthol versus non-menthol smokers...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BMJ Publishing Group
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051549/ https://www.ncbi.nlm.nih.gov/pubmed/35487522 http://dx.doi.org/10.1136/bmjopen-2021-058823 |
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author | Cohn, Amy M Pickworth, Wallace Audrain-McGovern, Janet Murphy, James Villanti, Andrea C Hedeker, Donald Dunn, Delaney Wyatt, Riley Niznik, Taylor Cotten, Whitney Smith, Michael Ehlke, Sarah J |
author_facet | Cohn, Amy M Pickworth, Wallace Audrain-McGovern, Janet Murphy, James Villanti, Andrea C Hedeker, Donald Dunn, Delaney Wyatt, Riley Niznik, Taylor Cotten, Whitney Smith, Michael Ehlke, Sarah J |
author_sort | Cohn, Amy M |
collection | PubMed |
description | INTRODUCTION: Although the Food and Drug Administration banned other characterising flavours in cigarettes, menthol cigarettes are still available to consumers. Young adult new smokers are initiating with menthol cigarettes, such that the prevalence of young adults menthol versus non-menthol smokers is increasing. Experimentation with menthol cigarettes is associated with progression to regular smoking and nicotine dependence. This ongoing clinical trial in young adult smokers measures appeal and the reinforcing value of smoking menthol versus non-menthol cigarettes and the impact of these variables on changes in smoking behaviour at a 6-month follow-up. METHODS AND ANALYSIS: Reinforcement for menthol smoking is assessed in the laboratory using a validated behavioural economic choice task, and appeal is measured in the natural environment using ecological momentary assessment (EMA). Analyses will examine differences between menthol and non-menthol cigarette smoking on measures of subjective response in the laboratory and via EMA, and how subjective response mediates the association between menthol preference at baseline and smoking outcomes at follow-up. ETHICS AND DISSEMINATION: This protocol was approved by the University of Oklahoma Health Sciences Center Institutional Review Board (#10581). The findings will isolate the unique effects of menthol in smoking and will help inform regulatory decisions about the abuse liability of menthol cigarettes. Findings will be disseminated through peer-reviewed journal articles and presentations at national and international conferences. TRIAL REGISTRATION NUMBER: NCT03953508. |
format | Online Article Text |
id | pubmed-9051549 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | BMJ Publishing Group |
record_format | MEDLINE/PubMed |
spelling | pubmed-90515492022-05-06 Measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (PRISM) Cohn, Amy M Pickworth, Wallace Audrain-McGovern, Janet Murphy, James Villanti, Andrea C Hedeker, Donald Dunn, Delaney Wyatt, Riley Niznik, Taylor Cotten, Whitney Smith, Michael Ehlke, Sarah J BMJ Open Addiction INTRODUCTION: Although the Food and Drug Administration banned other characterising flavours in cigarettes, menthol cigarettes are still available to consumers. Young adult new smokers are initiating with menthol cigarettes, such that the prevalence of young adults menthol versus non-menthol smokers is increasing. Experimentation with menthol cigarettes is associated with progression to regular smoking and nicotine dependence. This ongoing clinical trial in young adult smokers measures appeal and the reinforcing value of smoking menthol versus non-menthol cigarettes and the impact of these variables on changes in smoking behaviour at a 6-month follow-up. METHODS AND ANALYSIS: Reinforcement for menthol smoking is assessed in the laboratory using a validated behavioural economic choice task, and appeal is measured in the natural environment using ecological momentary assessment (EMA). Analyses will examine differences between menthol and non-menthol cigarette smoking on measures of subjective response in the laboratory and via EMA, and how subjective response mediates the association between menthol preference at baseline and smoking outcomes at follow-up. ETHICS AND DISSEMINATION: This protocol was approved by the University of Oklahoma Health Sciences Center Institutional Review Board (#10581). The findings will isolate the unique effects of menthol in smoking and will help inform regulatory decisions about the abuse liability of menthol cigarettes. Findings will be disseminated through peer-reviewed journal articles and presentations at national and international conferences. TRIAL REGISTRATION NUMBER: NCT03953508. BMJ Publishing Group 2022-04-27 /pmc/articles/PMC9051549/ /pubmed/35487522 http://dx.doi.org/10.1136/bmjopen-2021-058823 Text en © Author(s) (or their employer(s)) 2022. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ. https://creativecommons.org/licenses/by-nc/4.0/This is an open access article distributed in accordance with the Creative Commons Attribution Non Commercial (CC BY-NC 4.0) license, which permits others to distribute, remix, adapt, build upon this work non-commercially, and license their derivative works on different terms, provided the original work is properly cited, appropriate credit is given, any changes made indicated, and the use is non-commercial. See: http://creativecommons.org/licenses/by-nc/4.0/ (https://creativecommons.org/licenses/by-nc/4.0/) . |
spellingShingle | Addiction Cohn, Amy M Pickworth, Wallace Audrain-McGovern, Janet Murphy, James Villanti, Andrea C Hedeker, Donald Dunn, Delaney Wyatt, Riley Niznik, Taylor Cotten, Whitney Smith, Michael Ehlke, Sarah J Measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (PRISM) |
title | Measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (PRISM) |
title_full | Measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (PRISM) |
title_fullStr | Measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (PRISM) |
title_full_unstemmed | Measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (PRISM) |
title_short | Measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (PRISM) |
title_sort | measuring young adult appeal for menthol and non-menthol cigarettes: protocol of a clinical trial using both laboratory and intensive longitudinal methods (prism) |
topic | Addiction |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051549/ https://www.ncbi.nlm.nih.gov/pubmed/35487522 http://dx.doi.org/10.1136/bmjopen-2021-058823 |
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