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Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction
“Calcium hydroxide [Ca(OH)(2)]” is a medicament frequently used for antimicrobial purposes in endodontic procedures, or it is used as a toxic-waste adsorbent in industry. Ca(OH)(2) particles produced through conventional methods are size untunable and have a wide size distribution and polygonal shap...
Autores principales: | , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Royal Society of Chemistry
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051553/ https://www.ncbi.nlm.nih.gov/pubmed/35493011 http://dx.doi.org/10.1039/d0ra01275k |
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author | Yang, Chih-Hui Wang, Ya-Chin Wang, Ta-Chen Chang, Yi-Ching Lin, Yun-Chul Chen, Pei-Fan Huang, Wei-Jie Wen, Hsin-Yi Lin, Yu-Mei Kuo, Wen-Shuo Wang, Yi-Ting Huang, Keng-Shiang |
author_facet | Yang, Chih-Hui Wang, Ya-Chin Wang, Ta-Chen Chang, Yi-Ching Lin, Yun-Chul Chen, Pei-Fan Huang, Wei-Jie Wen, Hsin-Yi Lin, Yu-Mei Kuo, Wen-Shuo Wang, Yi-Ting Huang, Keng-Shiang |
author_sort | Yang, Chih-Hui |
collection | PubMed |
description | “Calcium hydroxide [Ca(OH)(2)]” is a medicament frequently used for antimicrobial purposes in endodontic procedures, or it is used as a toxic-waste adsorbent in industry. Ca(OH)(2) particles produced through conventional methods are size untunable and have a wide size distribution and polygonal shape. In this paper, a novel and facile approach involving template-mediated synthesis and two-step ion exchange is proposed for uniform size Ca(OH)(2) composite particles generation. “Sodium-alginate (Na-alginate)” was used as a precursor, and monodisperse Na-alginate emulsions were formed through needle droplet or droplet microfluidic technology. After the first ion exchange step with the Ca(2+) ions, “calcium-alginate (Ca-alginate)” particles were obtained. The Ca-alginate particles were intermediate reaction products and were designed to be the templates for ensuring the spherical shape and size of products. The OH(−) ions were used for the second ion exchange step to fabricate Ca(OH)(2) composite particles. The results revealed that the Ca(OH)(2) composite particles were size tunable, had a spherical shape, and were monodisperse (with a relative standard deviation of less than 8%). The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay revealed that the Ca(OH)(2) composite particles were potential biocompatible materials. |
format | Online Article Text |
id | pubmed-9051553 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | The Royal Society of Chemistry |
record_format | MEDLINE/PubMed |
spelling | pubmed-90515532022-04-29 Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction Yang, Chih-Hui Wang, Ya-Chin Wang, Ta-Chen Chang, Yi-Ching Lin, Yun-Chul Chen, Pei-Fan Huang, Wei-Jie Wen, Hsin-Yi Lin, Yu-Mei Kuo, Wen-Shuo Wang, Yi-Ting Huang, Keng-Shiang RSC Adv Chemistry “Calcium hydroxide [Ca(OH)(2)]” is a medicament frequently used for antimicrobial purposes in endodontic procedures, or it is used as a toxic-waste adsorbent in industry. Ca(OH)(2) particles produced through conventional methods are size untunable and have a wide size distribution and polygonal shape. In this paper, a novel and facile approach involving template-mediated synthesis and two-step ion exchange is proposed for uniform size Ca(OH)(2) composite particles generation. “Sodium-alginate (Na-alginate)” was used as a precursor, and monodisperse Na-alginate emulsions were formed through needle droplet or droplet microfluidic technology. After the first ion exchange step with the Ca(2+) ions, “calcium-alginate (Ca-alginate)” particles were obtained. The Ca-alginate particles were intermediate reaction products and were designed to be the templates for ensuring the spherical shape and size of products. The OH(−) ions were used for the second ion exchange step to fabricate Ca(OH)(2) composite particles. The results revealed that the Ca(OH)(2) composite particles were size tunable, had a spherical shape, and were monodisperse (with a relative standard deviation of less than 8%). The 3-(4,5-dimethylthiazol-2-yl)-2,5-diphenyl tetrazolium bromide (MTT) assay revealed that the Ca(OH)(2) composite particles were potential biocompatible materials. The Royal Society of Chemistry 2020-04-03 /pmc/articles/PMC9051553/ /pubmed/35493011 http://dx.doi.org/10.1039/d0ra01275k Text en This journal is © The Royal Society of Chemistry https://creativecommons.org/licenses/by-nc/3.0/ |
spellingShingle | Chemistry Yang, Chih-Hui Wang, Ya-Chin Wang, Ta-Chen Chang, Yi-Ching Lin, Yun-Chul Chen, Pei-Fan Huang, Wei-Jie Wen, Hsin-Yi Lin, Yu-Mei Kuo, Wen-Shuo Wang, Yi-Ting Huang, Keng-Shiang Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction |
title | Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction |
title_full | Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction |
title_fullStr | Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction |
title_full_unstemmed | Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction |
title_short | Facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction |
title_sort | facile synthesis of highly tunable monodispersed calcium hydroxide composite particles by using a two-step ion exchange reaction |
topic | Chemistry |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9051553/ https://www.ncbi.nlm.nih.gov/pubmed/35493011 http://dx.doi.org/10.1039/d0ra01275k |
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